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This is a review of the Pragmatic Trial Examining Oxygenation Prior to Intubation (PREOXI) trial(1). (12 minute read)

The aim of this trial was to determine to determine the effect of preoxygenation with noninvasive ventilation, compared to oxygen mask, on the incidence of hypoxemia during tracheal intubation.

What They Did

This was a pragmatic, multicenter, unblinded, randomized, parallel-group trial, conducted at 24 sites (7 emergency departments and 17 ICUs) in critically ill adults, undergoing tracheal intubation.

N = 1301

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