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The Study
Kim J-S et al. Diastolic Blood Pressures and end tidal carbon dioxides during cardiopulmonary resuscitations and their association with outcomes in adult out-of-hospital cardiac arrest patients: A preplanned secondary analysis of the Augmented Medication CardioPulmonary resuscitation (AMCPR) trial. Resuscitation 210 (2025) 110537. Ahead  of Print.

During cardiac arrest, Diastolic blood pressure of >25 mm Hg is often targetted to perfuse coronary vessels. However exact targets are not known. Similarly we use end-tidal CO2 as a surrogate marker of cardiac output.

This study looked at specific targets of diastolic blood pressure to achieve ROSC.

What They Did

This was a preplanned sub-study of the AMCPR trial;  a randomized clinical trial of 180 patients with out of hospital cardiac arrest (OHCA) and invasive DBP monitoring during resuscitation. A further 84 patients were added to the original review.

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