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Do steroids decrease mortality in patients with severe community acquired pneumonia?

Community acquired pneumonia is the leading cause of death from infection, approaching 10% mortality. In those patients who are mechanically ventilated, mortality may be as high as 30%. Glucocorticoids have been associated with positive effects in community acquired pneumonia, however they have not been shown to change mortality.

Dequin PF et al (1) conducted the Community-Acquired Pneumonia: Evaluation of Corticosteroids (CAPE COD) Trial.

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